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Nginx from the 0.7.48 release, support for Squid cache similar function. This cache is used as the URL and the relevant combination of Key, with the md5 hash code and saved on the hard drive, so it can support any URL link, also supports 404/301/302 such non-200 status code. Although the official Nginx Web caching service can only status code for the specified URL or set an expiration time, like Squid does not support the PURGE command to manually clear the cache page specified, but Nginx module by a third party, you can clear the cache of the specified URL .
Nginx’s Web caching services are mainly related to the instruction set and fastcgi_cache proxy_cache related instruction set composition, the former agent for the reverse, on the back-end content source server cache, which is mainly used to cache the FastCGI dynamic process. Both features are basically the same.
The latest version of Nginx 0.8.32, proxy_cache and fastcgi_cache been more perfect, with a third party ngx_cache_purge module (used to clear the cache of the specified URL), they can already completely replace the Squid. We have used in the production environment, the proxy_cache Nginx caching more than two months, very stable, speed is not inferior to Squid.
In function, Nginx have already have Squid Web cache acceleration, clear the cache function of the specified URL. In performance, Nginx on the use of multi-core CPU is better than a lot of Squid. In addition, the reverse proxy, load balancing, health checks, back-end server fail, Rewrite rewrite, ease of use, Nginx much stronger than the Squid. This makes a Nginx may also be a "load-balancing server" and "Web cache server" to use.

Install Part:

1.download purge patch for nginx and unzip it
wget http://labs.frickle.com/files/ngx_cache_purge-1.0.tar.gz
tar zxvf ngx_cache_purge-1.0.tar.gz

2.download nginx and unzip nginx
wget http://nginx.org/download/nginx-0.8.32.tar.gz
tar zxvf nginx-0.8.32.tar.gz

3.compile nginx
cd nginx-0.8.32/
./configure –user=www –group=www –add-module=../ngx_cache_purge-1.0 –prefix=/opt/nginx –with-http_stub_status_module –with-http_ssl_module
make && make install
cd /opt/nginx/conf

4.modify config file nginx.conf

user  www www;
worker_processes 8;
error_log  /opt/nginx/logs/nginx_error.log  crit;
pid        /opt/nginx/nginx.pid;
worker_rlimit_nofile 65535;

events
{
  use epoll;
  worker_connections 65535;
}

http
{
  include       mime.types;
  default_type  application/octet-stream;

  #charset  utf-8;

  server_names_hash_bucket_size 128;
  client_header_buffer_size 32k;
  large_client_header_buffers 4 32k;
  client_max_body_size 300m;
  sendfile on;
  tcp_nopush     on;
  keepalive_timeout 60;
  tcp_nodelay on;

  client_body_buffer_size  512k;
  proxy_connect_timeout    5;
  proxy_read_timeout       60;
  proxy_send_timeout       5;
  proxy_buffer_size        16k;
  proxy_buffers            4 64k;
  proxy_busy_buffers_size 128k;
  proxy_temp_file_write_size 128k;

#gzip on;
#gzip_min_length  1k;
#gzip_buffers     4 16k;
#gzip_http_version 1.1;
#gzip_comp_level 2;
#gzip_types       text/plain application/x-javascript text/css application/xml;
#gzip_vary on;

proxy_temp_path   /data/proxy_temp_dir;
proxy_cache_path  /data/proxy_cache_dir  levels=1:2   keys_zone=cache_one:500m inactive=1d max_size=20g;

upstream backend_server {
  server   192.168.1.38:80 weight=1 max_fails=2 fail_timeout=30s;
}

server
{
  listen       80;
  server_name  www.test.com *.test.com;
  index index.html index.htm index.php;

  location /
  {
       proxy_next_upstream http_502 http_504 error timeout invalid_header;
       proxy_cache cache_one;
       proxy_cache_valid  200 304 12h;

       proxy_cache_key $host$uri$is_args$args;
       proxy_set_header Host  $host;
       proxy_set_header X-Forwarded-For  $remote_addr;
       proxy_pass http://backend_server;
       expires      1d;
  }

  location ~ /purge(/.*)
  {
   allow            127.0.0.1;
   allow            192.168.1.253;
   deny             all;
   proxy_cache_purge    cache_one   $host$1$is_args$args;
    }

    location ~ .*\.(php|jsp|cgi)?$
    {
         proxy_set_header Host  $host;
         proxy_set_header X-Forwarded-For  $remote_addr;
         proxy_pass http://www.test.com;
    }

    access_log  off;
  }
}

5. Nginx start script nginx-start.sh
#!/bin/sh
ulimit -SHn 65535
/opt/nginx/sbin/nginx

chmod +x nginx-start.sh
./nginx-start.sh

6.Clean special url

you can visit page to delete

upload/thumb/20101101/201011011126134751_120_90.jpg  file.
http://www.test.com/purge/upload/thumb/20101101/201011011126134751_120_90.jpg

Return Result

Successful purge

Key : www.test.com/upload/thumb/20101101/201011011126134751_120_90.jpg
Path: /data/proxy_cache_dir/0/98/d0a52447df34c0d5abe1cf34b4bf0980

nginx/0.8.32